FIGURE

Fig. S3

ID

ZDB-FIG-140701-10

Publication

Aigler et al., 2014 - Selection and constraint underlie irreversibility of tooth loss in cypriniform fishes

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Fig. S3

Tooth rudiments are absent from the upper pharynx of wild-type zebrafish. Ectodysplasin A receptor (edar) expression is limited to tooth germs (arrows) of the lower pharynx in wild-type (A and C) but is induced in upper pharyngeal epithelium (arrowheads) and upper pharyngeal tooth germs (arrowheads) of the ef1α:eda transgenic (B and D). Expression of the transcription factor pitx2 is found in lower pharyngeal tooth germs (arrows) and upper pharyngeal epithelium (arrowheads) at 60 hpf in the wild-type (E) and ef1α:eda transgenic (F). Expression of this gene becomes restricted to lower pharyngeal tooth germs (arrows) at 72 hpf in the wild-type (G), but is also expressed in upper pharyngeal tooth germs (arrowheads) in the ef1α:eda transgenic (H). Abbreviations: hpf, hours postfertilization; n, notochord; y, yolk. (Scale bars, 50 μm.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA