FIGURE

Fig. 6

ID

ZDB-FIG-140221-4

Publication

Drummond et al., 1998 - Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function

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Fig. 6

Cystic maldevelopment in zebrafish pronephric mutants. (A) The mutant double bubble (dbb^m153) emerges from its chorion with a ventrally curved body axis and within 3-4 hours bilateral pronephric cysts (arrow in B) are evident. (C) Cross section of wildtype pronephros at 3.5 days pf. (D) Section of dbb^m468 showing a grossly distended pronephric cyst in place of the pronephric tubule and a glomerulus reduced to a flattened septum at the midline. (E) The mutant fleer (flr) shows less severe cyst distension despite a flattened pronephric tubule epithelium and also a marked distension of the glomerular capillaries. (F) pao pao tang (pap) has an apparently intact glomerulus while the pronephric tubule epithelium is flattened and the pronephric duct is also distended. gl, glomerulus; pt, pronephric tubule; pd, pronephric duct.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dbl^m153 (AB) ift70^m477 (AB) pap^m629 (AB) wlk^m478 (AB)
Observed In:	glomerular capillary pronephric duct pronephric glomerulus pronephric tubule pronephric tubule epithelium pronephros whole organism
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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