Fig. 9
Knockdown of cx43 rescues evx1 expression in alf dty86. (A) Whole mount ISH of evx1 shows that evx1 is expressed in most fin rays in cx43-morpholino (MO) fins (on) but not in cx43-mismatch (MM) fins (off). Arrows identify evx1-positive signal. (B) evx1 expression is present in a much higher percentage of fin rays in alf dty86 following injection/electroporation of cx43-MO compared with either the cx43-MM control fins or the uninjected fin rays. Statistical significance (*) was determined by student’s t-test where p<0.05 show significant differences. The p-value for the comparison of cx43-MO and cx43-MM was p = 0.0015. The p-value for the comparison of cx43-MO and uninjected fin rays was p = 0.0036. The bars represent the standard deviation. |
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Stage: | Adult |