FIGURE

Fig. S5

ID

ZDB-FIG-140107-9

Publication

McMillan et al., 2013 - Regeneration of breeding tubercles on zebrafish pectoral fins requires androgens and two waves of revascularization

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Fig. S5

Estradiol and flutamide inhibit BT regeneration and growth in the male pectoral fins. (A,C,E,G,I,K,M,O,Q,U,S,W) BTs along the anterior rays of control intact and regenerating fins. In some cases BT clusters are observed on dorsal and ventral surfaces of the fin rays (white arrowheads in (O)). (B,D,F,H,J,L) Treatment with flutamide (14 dot) results in smaller BTs on the intact fin/stump and no BTs on the fin regenerate. (N,P,R,T,V,X) E2 treatment (18 dot) results in BTs that are reduced in size in the intact fin and regenerate stump and no BTs in the regenerate. White vertical lines indicate amputation plane. Scale bar for all panels = 100μm (shown in A). B.F. = Brightfield; Fluo = KR21/RFP; Merge = Brightfield +KR21/RFP.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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