FIGURE

Fig. 1

ID

ZDB-FIG-131231-37

Publication

van der Velden et al., 2013 - The polycomb group protein ring1b/rnf2 is specifically required for craniofacial development

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Fig. 1

Ring1b mutants lack almost all head cartilage elements.

Lateral view of WT and ring1b live embryos at 72 hpf (A, B). Alcian-Blue stained head cartilages of WT (C, E, G and H) and ring1b (D, F, H and J) mutants at the indicated developmental points, ventral views. The paired trabeculae have elongated and fused posteriorly in WT embryos at 56 hpf (E) and by 72 hpf the elaborate cartilagenous skeleton of the head has been established (I). In contrast, no cartilage is visible in ring1b mutants except for two minute cartilage deposits at 72 hpf ring1b mutants (J: arrowheads). ch: ceratohyal; ep: ethmoid plate; hys: hyosymplectic; m: Meckel’s cartilage; pc: parachordal, pq: palatoquadrate; tc: trabeculae.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	rnf2^ibl30/ibl30 rnf2^ibl31/ibl31
Observed In:	ceratohyal cartilage embryonic neurocranium morphogenesis embryonic viscerocranium morphogenesis ethmoid cartilage head hyosymplectic cartilage Meckel's cartilage mesocoracoid cartilage neurocranial trabecula palatoquadrate cartilage parachordal cartilage pectoral fin scapulocoracoid
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

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