FIGURE

Fig. 1

ID

ZDB-FIG-130719-12

Publication

Neal et al., 2013 - H. pylori Virulence Factor CagA Increases Intestinal Cell Proliferation by Wnt Pathway Activation in a Transgenic Zebrafish Model

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Fig. 1

Development of CagA+ transgenic zebrafish. (A) Ubiquitous CagA-EGFP fusion protein expression driven by the b-actin promoter. (B) Ubiquitous CagA^EPISA-EGFP fusion protein expression driven by the b-actin promoter. (C) Intestinal CagA-EGFP fusion protein expression driven by the i-fabp promoter. (D) RT-PCR of dissected larval intestine showing expression of cagA and the housekeeping control gene RPL13 at 6 dpf. (E) Quantitative RT-PCR of dissected adult intestines showing relative expression levels of cagA transcript in transgenic lines at 1 year of age. Expression levels were normalized to SDHA and β-actin; bars indicate mean ± s.d. of biological triplicates. Scale bars: 500 μm.

Expression Data

Gene:	EGFP
Fish:	b1231Tg b1232Tg b1233Tg
Anatomical Terms:	intestine whole organism
Stage:	Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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