FIGURE

Fig. 3

ID

ZDB-FIG-130624-3

Publication

Kamm et al., 2013 - The Developmental Brain Gene NPAS3 Contains the Largest Number of Accelerated Regulatory Sequences in the Human Genome

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

The NPAS3 gene contains the largest number of HAEs. In the central panel, schematic drawing modified from the UCSC genome browser, showing the NPAS3 locus in genomic context on chromosome 14q13.1. Below, the four splicing variants of the NPAS3 gene are shown. The coloured bars indicate the location of the 14 HAEs. Blue bars indicate HARs (Pollard, Salama, King, et al. 2006; Pollard, Salama, Lambert, et al. 2006); green bars indicate HACNS (Prabhakar et al. 2006); and red bars show 29-mammals HARs (2× HAR; Lindblad-Toh et al. 2011). The overlapping HAE is shown by a green–blue bar. On top and below of the central panel, fluorescent and bright field microphotographs showing representative transgenic zebrafish of each HAE expressing EGFP at 24 hpf (H, I, J, K, L, M, N, O, P, Q, R, S, T, and U) and 48 hpf (A, B, C, D, E, F, G, V, W, X, Y, Z, AA, and BB). Small boxes (U and BB) represent 250 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol. Biol. Evol.