FIGURE

Fig. 5

ID

ZDB-FIG-130109-53

Publication

Yanicostas et al., 2012 - Requirement for zebrafish ataxin-7 in differentiation of photoreceptors and cerebellar neurons

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Fig. 5

Moderate zebrafish atxn7 depletion impairs the differentiation of cerebellar neurons.

Dorsal views of dissected brains from 5 dpf 1 pmol mmMOzatxn^AUG (A, A′, A′′, A′′′, C, C′ and C′′) and 0.3 pmol MOzatxn7^SPL morphants (B, B′, B′′, B′′′, D, D′ and D′′). DAPI staining (A and B), Pav7 immunostaining of Purkinje cells (A′, B′, C and D) and Vglut1 immunostaining of granule cells (A′′, B′′, C′ and D′). Anterior is to the left. Enlarged views of the brains showed in A′ (C), A′′ (C′), A′′′ (C′′), B′ (D), B′′ (D′), and B′′′ (D′′). Merge images of the photographs A′ and A′′ (A′′′), B′ and B′′ (B′′′), C and C′ (C′′), and D and D′ (D′′).

Expression Data

Gene:	pvalb7
Antibodies:	Ab1-pvalb7 Ab1-slc17a7
Fish:	AB AB + MO2-atxn7
Knockdown Reagent:	MO2-atxn7
Anatomical Terms:	cerebellar granule cell Purkinje cell
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO2-atxn7
Knockdown Reagent:	MO2-atxn7
Observed In:	Purkinje cell
Stage:	Day 5

Phenotype Detail

Acknowledgments

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