FIGURE

Fig. 1

ID

ZDB-FIG-121116-42

Publication

Tessadori et al., 2012 - Identification and functional characterization of cardiac pacemaker cells in zebrafish

Other Figures

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Fig. 1

Characterization of the embryonic Isl1^-/- cardiac phenotype in vivo.

(A) Zebrafish embryonic heart at 2 dpf. The embryonic heart is highlighted in black dotted contour; white dotted lines through the atrium (A) and the ventricle (V) are placed at kymograph positions. (B) Atrial (A) and ventricular (V) kymographs from 2 dpf embryonic hearts spanning approximately 2.8 s. Note the much longer period of the Isl^-/- heart when compared to the sibling and the irregularity of the period (double arrow and white dotted vertical lines). Movies are available as Movies S1 and S2, respectively. (C) Box-whisker plots representation of 20 successive heartbeats of 2 dpf Isl1^-/- and sibling embryos. (D) Kymograph recorded at 3 dpf covering a period of about 16 s of absent heart contractions. For all panels a: atrium; v: ventricle.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	isl1a^sa29/sa29
Observed In:	heart contraction
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

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