FIGURE

Fig. S3

ID

ZDB-FIG-121105-11

Publication

Bräutigam et al., 2011 - Vertebrate-specific glutaredoxin is essential for brain development

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Fig. S3

Neuronal apoptosis in embryos is specific for the lack of zebrafish (zf) glutaredoxin (Grx) 2. Costaining of neurons (anti-HuC/D antibody, red) and apoptotic cell death (TUNEL assay, blue) at 24 hours post fertilization (hpf) in embryos with blocked zfGrx2 expression. (A) Apoptosis at 24 hpf in the CNS of embryos lacking zfGrx2 detected by active caspase-3 measurements was rescued by injection of 20 pgembryo capped zfGrx2 mRNA simultaneously to morpholino injection.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-glrx2
Knockdown Reagent:	MO1-glrx2
Observed In:	hindbrain neuron spinal cord
Stage:	Prim-5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA