FIGURE

Fig. 7

ID

ZDB-FIG-120216-96

Publication

Goonesinghe et al., 2012 - Desmosomal cadherins in zebrafish epiboly and gastrulation

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Fig. 7

Knockdown of desmosomal cadherins affects gastrulation movements. In situ hybridisation images for gata1 at 30% epiboly (A) and myod, krox20 (B) at tailbud stage for both zfDsc1 and zfDsg2a morphant embryos. WT embryos are shown for comparison. A.i. and A.ii. show the lateral (Lat) and animal pole (AP) views, respectively. Circles indicate the expanded expression of gata1 in the germ ring margin of the morphants. B.i. and B.ii. show the dorsal (Dor) and lateral (Lat) views, respectively. Double headed arrows in B.i. indicate medio-lateral expansion of the distance between krox20 markers (pointed arrows) and myod marker (blunted arrows). Short arrows in B.ii show reduced rostro-caudal extension as indicated by the myod marker.

Expression Data

Genes:	egr2b gata1a myod1
Fish:	TL TL + MO1-dsg2.1 TL + MO4-dsc2l
Knockdown Reagents:	MO1-dsg2.1 MO4-dsc2l
Anatomical Terms:	ectoderm margin paraxial mesoderm
Stage Range:	30%-epiboly to Bud

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.