Fig. S1
- ID
- ZDB-FIG-111215-22
- Publication
- Nguyen et al., 2011 - A high level of liver-specific expression of oncogenic KrasV12 drives robust liver tumorigenesis in transgenic zebrafish
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Morphological development of liver in transgenic fish expressing EGFP-krasV12. Comparison of liver morphogenesis between LiPan control [Tg(fabp10:dsRFP; elaA:EGFP)] zebrafish (A-D) and two representative cases of abnormal liver morphology distinguished by different degrees of liver enlargement/hyperplasia at the early stages (E-H and I-L) observed in the F1/I Tg(fabp10:EGFP-krasV12) zebrafish. Note that there were no obvious differences between these two cases at the later stages. (A,E,I) 7 dpf (day post-fertilization); (B,F,J) 15 dpf; (C,G,K) 30 dpf; (D,H,L) 90 dpf. All big images are lateral view whereas all insets are ventral view. |