FIGURE

Fig. 1

ID

ZDB-FIG-111129-24

Publication

Goudevenou et al., 2011 - Def6 Is Required for Convergent Extension Movements during Zebrafish Gastrulation Downstream of Wnt5b Signaling

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Fig. 1

Zebrafish def6 is dynamically expressed during development.

(A) Schematic representation of the def6 protein domain arrangement consisting of an N-terminal putative Ca²⁺-binding EF-hand domain followed by a def6/swap-70 homology (DSH), a pleckstrin-homology (PH) domain and a C-terminal Dbl-homology-like (DHL) domain. (B) Sequence identity and similarity of the various def6 domains between different species as indicated. (C-E) Def6 is ubiquitously expressed at the (C) 8-cell stage, (D) 40% epiboly and (E) 80% epiboly stages. (F) At 24hpf, def6 transcripts are found in the developing brain, somite boundaries and tail. (G) The expression pattern of def6 becomes more restricted at 3dpf where mRNA can be detected in the pharyngeal arches, medial and pectorial fins and anterior and posterior neuromasts of the lateral line.

Expression Data

Gene:	def6a
Fish:	WT
Anatomical Terms:	anterior lateral line neuromast brain median fin pectoral fin pharyngeal arch post-vent region posterior lateral line neuromast somite border whole organism
Stage Range:	8-cell to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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