FIGURE

Fig. 3

ID

ZDB-FIG-111013-10

Publication

Waskiewicz et al., 2001 - Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning

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Fig. 3

Inhibition of Meis function results in reduced krox20 expression in both wild-type and lzr mutant embryos, while overexpression of meis1.1WT partially rescues the lzr mutant phenotype. Each panel is oriented with anterior towards the left. (A-D) krox20 expression (in r3 and r5) in wild-type embryos at 8-10 somites injected with mRNAs shown on the left. Note the decrease in krox20 expression caused by Meis1.1ΔC and Meis1.1N323D in C,D, as compared with wild type in A. (E-H) krox20 expression in lzr^- embryos injected as shown. Note the increase in krox20 expression caused by expressing Meis1.1WT, by comparing E,F. Genotypes of embryos were determined subsequent to photography using PCR-mediated dHPLC (Pöpperl et al., 2000).

Expression Data

Gene:	egr2b
Fish:	pbx4^b557/b557
Anatomical Terms:	presumptive rhombomere 3 presumptive rhombomere 5 rhombomere 3 rhombomere 5
Stage Range:	5-9 somites to 10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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