FIGURE
Fig. 1
- ID
- ZDB-FIG-110817-11
- Publication
- Neumann et al., 2011 - Mutation in the type IB bone morphogenetic protein receptor alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish
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Fig. 1
The tgct mutants develop GCTs because of impaired germ-cell differentiation. Compared with adult wild-type males (A and C) (arrowhead: normal testis), adult tgct males display marked testicular enlargement (B and D) (arrow: testicular tumor). Wild-type testis (E) exhibits normal spermatogenesis (arrowhead: spermatogonia; arrow: spermatozoa). The tgct mutant testis (F) accumulates primitive germ cells. Although wild-type ovary (G) shows all stages of oocyte maturation up to mature stage IV oocytes, oocyte maturation is impaired in tgct homozygous females (H). [Scale bars: 100 μm (E and F); 50 μm (G and H).] |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Adult |
Phenotype Detail
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Full text @ Proc. Natl. Acad. Sci. USA