FIGURE

Fig. 6

ID

ZDB-FIG-110712-6

Publication

Slagle et al., 2011 - Nodal-Dependent Mesendoderm Specification Requires the Combinatorial Activities of FoxH1 and Eomesodermin

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Fig. 6

Eomes inhibition enhances the Nodal signaling and mesendoderm deficiencies of MZmid.

Markers for various populations of mesendoderm derivatives were analyzed in wild-type and MZmid embryos in which Eomes function was inhibited. Eomes inhibition in wild-type embryos has a minimal effect on expression of most markers, whereas in an MZmid background it has significant effects on mesendoderm-derived tissues, approaching MZoep levels for most markers. Arrowheads indicate Nodal-independent expression of bon in MZoep mutants.

Expression Data

Genes:	drl mixl1 noto pax2a tbx16 tbxta
Fish:	AB foxh1^pr1/pr1 tdgf1^tz257/tz257
Anatomical Terms:	margin mesoderm midbrain hindbrain boundary neural plate prechordal plate presumptive paraxial mesoderm presumptive shield ventral mesoderm
Stage Range:	30%-epiboly to 90%-epiboly

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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