FIGURE
Fig. 4
- ID
- ZDB-FIG-110221-23
- Publication
- Johnson et al., 2011 - mitfa is required at multiple stages of melanocyte differentiation but not to establish the melanocyte stem cell
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. 4
The vc7 allele affects spicing of mitfa. A) Electropherogram of sequence obtained from mitfavc7 allele. B) Location of vc7 mutation in genomic sequence. C) Semi-quantitative RT/PCR shows that missplicing is not temperature-sensitive. vc7 results in transcripts that (a) include intron 6 and (c) skip exon 6, in addition to correctly-spliced transcript (b). M, 200 basepair ladder; m, 100 basepair ladder. D) Reading frame is preserved in aberrantly-spliced transcripts a and c. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 350(2), Johnson, S.L., Nguyen, A.N., and Lister, J.A., mitfa is required at multiple stages of melanocyte differentiation but not to establish the melanocyte stem cell, 405-413, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.