Fig. S2
In spinal cord injury, foxj1a but not foxj1b is up-regulated. (A) foxj1a is expressed in the developing spinal cord, and is up-regulated 8 h after mechanical cord injury (arrowhead) induced with a forceps (B). Histological sections of control spinal cord (C) and injured spinal cord (D) reveals an injury-mediated increase in foxj1a in ciliated spinal cord cells. In contrast, foxj1b gene expression remains restricted to multiciliated cells of the pronephric duct in both control (E) and obstructed (F) embryos, and likewise remains restricted to the distal tip of the spinal cord in both spinal cord-intact (G) and spinal cord-injured (H) embryos. |