Distinct patterns of rhodopsin expression and retinotectal projections in dmbx1a and dmbx1b morphant embryos. Dorsal view anterior to the top of un-injected (A, B), MO1a injected (C, D), MO1b injected (E, F), and MO1a + MO1b injected (G, H) embryos demonstrating expression of rhodopsin (rho) (A, C, E, G) or the retinotectal projection pattern (green fluorescence) as defined in isl2b:GFP transgenic embryos (B, D, F, H). The mismatch control injected morpholinos resembled the un-injected controls and are not shown. In B, D, F, H, white arrow demarcates the terminal field of the retinal ganglion cells in the optic tectum and the white arrowhead demarcates axonal fibers of the optic nerve. MO, morpholino. Asterisk demarcates the region of trigeminal ganglion.
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