FIGURE

Fig. 3

ID
ZDB-FIG-101011-61
Publication
Oteiza et al., 2010 - Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ
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Fig. 3

PCP signalling regulates heart loop laterality in zebrafish. (A-C) Top view of 36 hpf pk1aMO-injected embryos showing expression of cardiac myosin light chain 2 (cmlc2) in the heart tube by wholemount in situ hybridisation. Arrows indicate the orientation of heart looping: normal loop to the right (A), absent loop (B) and inverted loop to the left (C). (D) Horizontal bar chart of the relative frequency of heart loop orientation (right loop, yellow; no loop, blue; left loop, red) scored in different experimental conditions (same conditions as in Fig. 1): control (n=122); slb (n=12); pk1a-MO 3 ng (n=137); MZppt (n=122); slb;ppt (n=50); pk1a-MO 1.5 ng (n=94); slb;pk1a-MO 1.5 ng (n=170); MZppt;pk1aMO 1.5 ng (n=60); pk1a-MO 3 ng DFC (n=46); and slb;pk1a-MO 4 ng DFC (n=56). Scale bar: 20 μm.

Expression Data
Gene:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: Prim-25

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Prim-25

Phenotype Detail
Acknowledgments
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