FIGURE

Fig. 1

ID

ZDB-FIG-100802-4

Publication

Zhao et al., 2010 - Klf6/copeb is required for hepatic outgrowth in zebrafish and for hepatocyte specification in mouse ES cells

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Fig. 1

copeb expression is enriched in endoderm organs during zebrafish development. (a) Total RNA was extracted from 10 embryos taken from the same clutch on 1–5 dpf was assessed for copeb RNA expression by qPCR relative to rppO by the ΔCt method. (b-g) copeb expression pattern in developing zebrafish embryos examined by WISH at 24 hpf, 36 hpf (c), 48 hpf (d), 60 hpf (e) 72 hpf (f) and 96 hpf (g). Structures previously shown to express copeb in the early embryo are labeled in b–d. Endoderm derived structures, including the gut (brackets), liver (white arrow) and swim bladder (black arrowhead) are labeled in e–g. Other structures expressing copeb are labeled. Scale bar = 100 microns.

Expression Data

Gene:	klf6a
Fish:	WT
Anatomical Terms:	brain eye gut hindbrain nucleus liver posterior lateral line ganglion swim bladder whole organism
Stage Range:	Prim-5 to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 344(1), Zhao, X., Monson, C., Gao, C., Gouon-Evans, V., Matsumoto, N., Sadler, K.C., and Friedman, S.L., Klf6/copeb is required for hepatic outgrowth in zebrafish and for hepatocyte specification in mouse ES cells, 79-93, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.