FIGURE

Fig. 5

ID

ZDB-FIG-100429-82

Publication

van Eekelen et al., 2010 - RPTPalpha and PTPepsilon Signaling via Fyn/Yes and RhoA is Essential for Zebrafish Convergence and Extension Cell Movements during Gastrulation

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Fig. 5

No cell specification defects in ptpra mutant or RPTPα and PTPε knockdown embryos. Embryos were fixed at 6 hpf and whole mount in situ hybridization was performed using probes for bmp2b, chordin (chd), gooscoid (gsc) or no tail (ntla). Embryos from ptpra^+/- incrosses were processed and genotyped after in situ hybridization. Alternatively, embryos injected at the 1-cell stage with ptpra-MO (0.3 ng/embryo) or ptpre-MO (2.5 ng ptprea-MO + 2.5 ng ptpreb-MO/embryo) were used. Each panel depicts on the left: animal pole view with dorsal to the right; on the right: lateral view with dorsal to the right. Scale bar = 250 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 340(2), van Eekelen, M., Runtuwene, V., Overvoorde, J., and den Hertog, J., RPTPalpha and PTPepsilon Signaling via Fyn/Yes and RhoA is Essential for Zebrafish Convergence and Extension Cell Movements during Gastrulation, 626-639, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.