FIGURE

Fig. 2

ID

ZDB-FIG-100209-7

Publication

Siddiqui et al., 2010 - The tight junction component Claudin E is required for zebrafish epiboly

Other Figures

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Fig. 2

Embryos injected with cldne-morpholino oligonucleotide (MO) exhibit epiboly delays. Lateral views of live embryos, injected construct indicated in lower right. A,B: Uninjected embryo at 30% epiboly (A), time matched cldne-MO injected embryo at sphere stage (B). C-E: Uninjected embryo at shield stage (C), time matched cldne-MO injected embryo at 40% epiboly (D), same embryo as in D (E), arrow indicates the yolk syncytial layer (YSL) nuclei, which have compacted normally. F: Shield stage embryo injected with mismatch morpholino. G: Shield stage embryo injected with cldne RNA. H: Rescued embryo injected with cldne RNA and cldne-MO. I,J: Uninjected embryo at 90% epiboly stage (I), time matched cldne-MO injected embryo at 70% epiboly (J).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-cldne
Knockdown Reagent:	MO1-cldne
Observed In:	dorsal convergence epiboly involved in gastrulation with mouth forming second external yolk syncytial layer involution involved in gastrulation with mouth forming second
Stage Range:	30%-epiboly to 90%-epiboly

Phenotype Detail

Acknowledgments

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