FIGURE

Fig. 4

ID

ZDB-FIG-091207-4

Publication

Furutani-Seiki et al., 1996 - Neural degeneration mutants in the zebrafish, Danio rerio

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Fig. 4

Class III mutant phenotypes. (A,B,E,G) Wild type; (C,D,F,H) yug embryos. (A-F) at 36 hours, (G,H) at 60 hours. (B,D) Acridine orange staining of A and C, respectively. (E,F) Parasagittal section of the brain. (A,C) The brain appears normal except for the presence of degenerating cells in yug embryos. (B,D) Apoptotic cells exist throughout the brain including the neural retina (arrowhead); acridine orange (AO)-staining of the olfactory epithelium (arrow) is reduced in yug; toluidine blue stained apoptotic cells are seen in the tectum in yug. The apoptotic cells are in a clump (arrow). Viable cells in the tectum are less well stained in yug embryos compared to wild type. The neuroepithelium is not differentiated properly (E,F). The head and eyes are small in yug embryos (G,H). Scale bar, 100 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	yug^tc1/tc1
Observed In:	apoptotic process brain brain cell eye head neuroepithelial cell optic tectum retinal neural layer spinal cord
Stage Range:	Prim-25 to Pec-fin

Phenotype Detail

Acknowledgments

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