FIGURE

Fig. 8

ID

ZDB-FIG-091113-117

Publication

Sanek et al., 2009 - Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression

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Fig. 8

Hh is necessary and sufficient for zic2a expression in the OS and ventral retina. (A-F) zic2a is expressed in the OS at 16s (A). In smo^-/- mutants, zic2a expression is reduced in the OS at this stage (B, 14/14 embryos, n=2), but not elsewhere. shha mRNA-injected WT embryos express zic2a ectopically in the OS and retina at 16s (C, 13/13 embryos, n=1). zic2a expression is still reduced in smo^-/- mutants at 19s (D,E, 30/30 embryos, n=2), and expanded in shha-injected retina (F, 19/19 embryos, n=1). The same result was observed at prim-5 (39/42 embryos, n=2, data not shown). Arrowheads point to the OS. Embryos are in lateral view, anterior to the left.

Expression Data

Gene:	zic2a
Fish:	AB smo^b641/b641
Anatomical Term:	optic stalk
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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