FIGURE

Fig. 1

ID

ZDB-FIG-081201-1

Publication

Esterberg et al., 2008 - Tailbud-derived Bmp4 drives proliferation and inhibits maturation of zebrafish chordamesoderm

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Fig. 1

Expansion of the tailbud in Fstl1/2 morphant embryos. (A-T) Expression of the tailbud markers spt (A-D), bmp4 (E-H), PSMAD1/5/8 (I-L) and eve1 (M-P), and the posterior axial marker admp (Q-T) in six-somite embryos injected with control morpholino (A,E,I,M,Q), fstl1/2 morpholino (B,F,J,N,R), fstl2 mRNA (C,G,K,O,S), and fstl1/2 morpholino and fstl2 mRNA (D,H,L,P,T). (U) Levels of PSMAD1/5/8, but not PSMAD2, are increased in Fstl1/2 morphants beginning at late gastrulation. All views except E-L are dorsal views, with anterior towards the top. (E-L) Lateral views, with anterior towards the left. Brackets illustrate the expression domain observed in control embryos. Arrows indicate the tailbud. Insets in E-H are views of the tailbud.

Expression Data

Genes:	admp bmp4 eve1 tbx16
Antibodies:	Ab-smad2 Ab3-smad
Fish:	WT WT + MO2-fstl1a + MO4-fstl1b
Knockdown Reagents:	MO2-fstl1a MO4-fstl1b
Anatomical Terms:	notochord posterior region tail bud whole organism
Stage Range:	75%-epiboly to 14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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