FIGURE

Fig. 1

ID

ZDB-FIG-081107-7

Publication

Kim et al., 2008 - Frizzled 8a function is required for oligodendrocyte development in the zebrafish spinal cord

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

fz8a expression revealed by in situ RNA hybridization. A,B: Dorsal views of the trunk region of whole embryos, anterior to the left. Arrowheads and brackets indicate expressions in the prechordal plate and medial neuroectoderm, respectively. C: Transverse sections, dorsal to the top, through the trunk region. Ventral neural keel (nk) cells, overlying notochord (nc), started to express fz8a at 14 hpf. D: Lateral view of the spinal cord of whole embryos, dorsal to the top and anterior to the left. Brackets indicate the expression of fz8a in the ventral spinal cord cells. E-H: Transverse sections of the spinal cord, dorsal to the top. E, F: fz8a-expressing cells occupy the ventral neural precursor cells. G: fz8a-expressing cells incorporate BrdU, as indicated by anti-BrdU antibody staining (red color), indicating that they are proliferating precursors. Arrows indicate fz8a⁺, BrdU⁺ neural precursor cells. H: fz8a-expressing cells confer olig2⁺ precursors, which are marked by EGFP fluorescence in the Tg(olig2:egfp) embryo. Arrows indicate fz8a⁺, olig2⁺ precursor cells in the ventral spinal cord.

Expression Data

Genes:	EGFP fzd8a
Antibody:	Ab-G3G4
Fish:	AB vu12Tg
Condition:	chemical treatment: 5-bromo-2'-deoxyuridine
Anatomical Terms:	neural keel neurectodermal cell neuroectoderm prechordal plate pronephric mesoderm spinal cord
Stage Range:	5-9 somites to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.