FIGURE

Fig. 3

ID

ZDB-FIG-081007-10

Publication

Huang et al., 2008 - Mypt1-mediated spatial positioning of Bmp2-producing cells is essential for liver organogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

sq181 mutant hepatoblasts are impaired in proliferation and subsequently undergo cell apoptosis that leads to a liverless phenotype. (A,B) Immunostaining using an anti-P-H3 antibody on (A) wild-type (wt) and (B) mutant (mu) zebrafish embryos at 30 hpf. (C,D) TUNEL assay of cell apoptosis in (C) wild-type and (D) mypt1^sq181 mutant embryos at 38 hpf. The white dotted line circles the liver primordium and the adjacent endoderm region.

Expression Data

Antibody:	Ab3-h3
Fish:	AB ppp1r12a^sq181/sq181 (AB)
Anatomical Terms:	brain liver
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ppp1r12a^sq181/sq181 (AB)
Observed In:	cell population proliferation hepatocyte lateral plate mesoderm liver hepatocyte liver development liver primordium
Stage Range:	Prim-15 to Prim-25

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development