Fig. 1

Wild-type and rose mutant adult D. rerio. (A) Wild-type adults exhibit several dark stripes comprising melanocytes and iridophores, with intervening light stripes comprising xanthophores and iridophores. (B–D) rose mutant adults have fewer melanocytes than wild-type, and these cells form stripes dorsally but spots ventrally. rose mutants also exhibit an iridophore defect, which is especially noticeable lateral to the gills (arrow) and over the abdomen. (B) rose^b140 adults exhibit a pigment pattern defect but are both viable and fertile as homozygotes. (C) rose^j3e1 adults exhibit a similar pigment pattern defect to rose^b140, but are severely runted. Shown is an individual comparable in age to that shown in (B). rose^j3e1 adults that attain larger sizes exhibit only a single dorsal melanocyte stripe and a fragmented ventral melanocyte stripe, as in rose^b140. (D) rose^j3e3 mutant adults have a marginally less severe melanocyte defect, typically having one additional melanocyte stripe compared to rose^b140 and rose^j3e1. Scale bar: 1 cm.