FIGURE

Fig. S3

ID

ZDB-FIG-080710-11

Publication

Martinez-Morales et al., 2005 - Differentiation of the vertebrate retina is coordinated by an FGF signaling center

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Fig. S3

Expression of Ath5 in zebrafish wt and Fgf mutant embryos. The temporal and spatial expression of Ath5 was examined in wild type (A,B,C), Ace/Fgf8 (D,E,F) and Lia/Fgf3 (G,H,I) mutant embryos. No significant difference was observed at 25 hpf and 28 hpf (A, D, G and B, E, H, respectively). However by 32 hpf a slight decrease in Ath5 expression was observed in Ace and Lia mutants (compare C with F and I). This could be due to a secondary developmental defect of these embryos or alternatively it would support a partially non-redundant role of Fgf8 and Fgf3 for the correct progression of Ath5 expression and retinal ganglion cell differentiation.

Expression Data

Gene:	atoh7
Fish:	AB fgf3^unspecified fgf8a^unspecified
Anatomical Terms:	presumptive neural retina retina
Stage Range:	Prim-5 to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Cell, 8(4), Martinez-Morales, J.R., Del Bene, F., Nica, G., Hammerschmidt, M., Bovolenta, P., and Wittbrodt, J., Differentiation of the vertebrate retina is coordinated by an FGF signaling center, 565-574, Copyright (2005) with permission from Elsevier. Full text @ Dev. Cell