FIGURE

Fig. 4

ID

ZDB-FIG-080620-10

Publication

Duan et al., 1999 - Insulin-like growth factor binding protein 2 is a growth inhibitory protein conserved in zebrafish

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Fig. 4

The expression of IGFBP-2 gene is increased by fasting and decreased by GH treatment in zebrafish. (A) Tissue distribution pattern of IGFBP-2 mRNA. Northern blot analysis of RNA samples isolated from 20-hr embryos (lane 1), whole body of adult zebrafish (lane 2), and brain (lane 3), eye (lane 4), ovary (lane 5), liver (lane 6), intestine (lane 7), muscle (lane 8) and fin (lane 9) collected from adult fish. (B) Effect of fasting on IGFBP-2 mRNA expression. RNA was isolated from fed (control) or fasted adult zebrafish. The values are means ± SE of three animals. *, P < 0.05 compared with the control. (C) Effect of GH on IGFBP-2 mRNA expression. Adult zebrafish were injected with pure seabass GH (1 μg/ml) or saline and sacrificed 15, 24, or 48 hr after the injection. The values are means ± SE of three animals. *, P < 0.05 compared with the control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA