FIGURE

Fig. 7

ID

ZDB-FIG-080506-7

Publication

Hong et al., 2008 - The Mych Gene Is Required for Neural Crest Survival during Zebrafish Development

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Fig. 7

Multiple defects in pharyngeal arch development caused by mych MO.
Control MO (A,C,E,G,I,K) and mych UTR MO-injected embryos (B,D,F,H,J,L). A–B. Lateral view of dlx2a expression in mych UTR MO-injected embryos at 26hpf (B). C–D. Ventral view of expression of hand2 at 36hpf. E–F. Ventral view of tbx1 expression at 45hpf. G–H. Lateral view of fli1-eGFP transgenic line at 40hpf. I–L. Lateral (I,J) and ventral (K,L) views of Alcian blue stained day 5 control (I,K) and mych UTR MO-injected embryos (J,L). ch, ceratohyal, b, branchial arch; e, ethmoid plate; g, gill arches; h, hyoid arch; hs, hyosymplectic; ht, heart; m, mandibular arch; mc, Meckel's cartilage; me, mesoderm; pec, pectoral fin; pq, palatoquadrate.

Expression Data

Genes:	dlx2a EGFP hand2 tbx1
Fish:	y1Tg/y1Tg AB y1Tg/y1Tg + MO1-mych AB + MO1-mych
Knockdown Reagent:	MO1-mych
Anatomical Terms:	heart tube mandibular arch skeleton mesoderm pharyngeal arch 2 skeleton pharyngeal arch 3 pharyngeal arch 3-7 pharyngeal arch 4 pharyngeal arch 5 pharyngeal arch 6
Stage Range:	Prim-5 to High-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	y1Tg/y1Tg + MO1-mych AB + MO1-mych
Knockdown Reagent:	MO1-mych
Observed In:	cranial cartilage endoderm development mesoderm development neurocranium pharyngeal arch 3-7 pharyngeal system development
Stage Range:	Prim-5 to Day 5

Phenotype Detail

Acknowledgments

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Open Access

Full text @ PLoS One