FIGURE

Fig. S2

ID

ZDB-FIG-080505-15

Publication

Snelson et al., 2008 - Tbx2b is required for the development of the parapineal organ

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Fig. S2

Parapineal migration is unaffected following disruption of the planar cell polarity pathway. (A-I) Dorsal views of the epithalamus in 24-hpf embryos (A-F) or 48-hpf larvae (G-I). Expression of otx5 (A-C) and tbx2b (D-F), and placement of the gfi1-positive parapineal cells (G-I), are unaffected in homozygous mutants for the planar cell polarity genes knypek (kny) or trilobite (tri). (J-Q) Lateral views of 24-hpf embryos. The Wnt receptor frz7a (blue) and the Wnt ligand wnt11 (blue) are excluded from the otx5-positive cells (red, arrowhead) of the pineal complex in WT (J-M) and fby mutant (N-Q) embryos. Scale bars: 25 μm in A-I,K,M,O,Q; 100 μm in J,L,N,P.

Expression Data

Genes:	fzd7a gfi1ab otx5 tbx2b wnt11f2
Fish:	WT gpc4^m119/m119 tbx2b^c144/c144 (AB) vangl2^m747/m747
Anatomical Terms:	parapineal organ pineal complex
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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