FIGURE

Fig. 1

ID

ZDB-FIG-080430-10

Publication

Ozbudak et al., 2008 - Notch Signalling Synchronizes the Zebrafish Segmentation Clock but Is Not Needed To Create Somite Boundaries

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Fig. 1

DAPT Treatment Blocks Notch Signalling Rapidly
DAPT causes loss of her4 expression (A) in the neural tube and (B) in the anterior PSM (where her4 is normally expressed in a faint but detectable stripe). Wild-type embryos were treated with 100 μm DAPT or with DMSO (control) medium for 1 h and stained by ISH for her4. In each panel, the DMSO control is shown on the left, the DAPT-treated embryo on the right. Treatment was begun at the 13-somite stage for (A) and at the 15-somite stage for (B). For each case, at least 14 embryos were examined, and typical specimens were selected for this illustration.

Expression Data

Gene:	her4.1
Fish:	WT
Condition:	chemical treatment: DAPT
Anatomical Terms:	neural tube segmental plate
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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