FIGURE

Fig. 5

ID

ZDB-FIG-080326-66

Publication

Pietri et al., 2008 - Six cadm/synCAM genes are expressed in the nervous system of developing zebrafish

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Fig. 5

Expression of cadms in the brain. A-R: In situ hybridization (ISH) staining in 48 hours postfertilization (hpf) zebrafish embryos; a dorsal view of whole-mount zebrafish (A-F), and cross-sections at the midbrain (G-L), and hindbrain (M-R) are presented for each cadm gene. Lines in A-F represent levels of the sections in G-L and M-R. S-X: cadm expression visualized in horizontal sections of adult brain. The cadm genes are expressed broadly in the developing and adult brain and show partially overlapping domains of expression. cadm2a is strongly expressed in the ventral medulla oblongata (MO) (arrowheads in O), while cadm2b is more diffuse in this region (asterisks in P). The posterior part of the MO shows strong staining for cadm1a (arrow in M). Ot, developing optic tectum; OT, optic tectum granular layer L3; Th, thalamus; TL, torus longitudinalis; Tu, tuberculum; VC, valvula cerebellis. Orientations are anterior at the top in A-F; dorsal at the top in G-R; anterior to the left in S-X. Scale bars = 50 μm in G-L, 50 μm in M-R, 0.5 mm in S-X.

Expression Data

Genes:	cadm1a cadm1b cadm2a cadm2b cadm3 cadm4
Fish:	WT
Anatomical Terms:	anterior lateral line ganglion caudal octavolateralis nucleus caudal parvocellular preoptic nucleus caudal tuberculum central caudal thalamic nucleus central nucleus inferior lobe central nucleus torus semicircularis corpus cerebelli corpus mamillare deep white zone descending octaval nucleus dorsal telencephalon dorsal thalamus epiphysis external cellular layer facial ganglion facial lobe glomerular layer glossopharyngeal ganglion granular eminence habenula hypophysis hypothalamus inferior lobe internal cellular layer lateral preglomerular nucleus magnocellular preoptic nucleus magnocellular superficial pretectal nucleus medial longitudinal fasciculus medial octavolateralis nucleus medulla oblongata nucleus isthmi nucleus lateralis valvulae olfactory bulb olfactory epithelium optic tectum periventricular grey zone periventricular nucleus posterior lateral line ganglion pretectal periventricular nucleus pretectum rostral octaval nucleus rostral parvocellular preoptic nucleus rostral preglomerular nucleus rostral thalamic nucleus spinal cord suprachiasmatic nucleus tegmentum torus lateralis torus longitudinalis torus semicircularis trigeminal ganglion vagal ganglion 1 vagal lobe valvula cerebelli ventral telencephalon ventral thalamus ventrolateral nucleus ventromedial thalamic nucleus
Stage Range:	Long-pec to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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