FIGURE

Fig. 1

ID

ZDB-FIG-080325-100

Publication

Yang et al., 2007 - Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo

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Fig. 1

Toxicants induce similar morphological changes in 120 hpf zebrafish embryos. Embryos were treated with (a) methylmercury chloride (60 μg/l, MeHg); (b) CdCl₂(5 mg/l, Cd); (c) PbCl₂(2.8 mg/l, Pb); (d) As₂O₃(79 mg/l, As); (e) Aroclor 1254 (33 mg/l, PCB); (f) acrylamide (71 mg/l, AA); (g) tert-butylhydroquinone (1.7 mg/l, tBHQ); (h) 4-chloroaniline (50 mg/l, 4CA); (i) 1,1-bis-(4-chlorophenyl)2,2,2-trichloroethane (15 mg/l, DDT); (j) 2,3,7,8-tetrachlorodibenzo-p-dioxin (500 ng/l, TCDD); (k) valproic acid (50 mg/l, VA); (l) vehicle 1 control (VC1): embryo water alone (for Cd, MeHg, Pb, As, VA, AA treatments); (m) vehicle 2 control (VC2): 0.2% ethanol control (for 4CA, DDT, tBHQ, PCB); (n) vehicle 3 control (VC3): 0.025% DMSO, 1.4 mg/l toluene (for TCDD). Embryos showed frequently a bent body axis and developed pericardial edema upon further cultivation.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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