FIGURE
Fig. 11
Fig. 11
Effect of yes antisense morpholino oligonucleotide injection on development. Embryos resulting from zygotes injected with 12.5 ng of the Yes antisense oligonucleotide exhibit normal development up to the sphere stage (a), but epiboly was defective and the normal embryonic germ layers were not formed (b). Embryos resulting from zygotes injected with 12.5 ng of the mutated control Yes antisense oligonucleotide (c–d) gastrulated normally. Scale bar = 300 μm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 277(1), Tsai, W.B., Zhang, X., Sharma, D., Wu, W., and Kinsey, W.H., Role of Yes kinase during early zebrafish development, 129-141, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.