FIGURE

Fig. 6

ID

ZDB-FIG-070821-3

Publication

Kelsh et al., 2000 - Genetic analysis of melanophore development in zebrafish embryos

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Fig. 6

spa^- embryos show reduced numbers and migration of melanoblasts. Lateral views of 2-dpf wild-type (A) and spa^- (B) embryos to show reduced numbers of ventral melanophores and an ectopic cluster behind otic vesicle (o). Wild types (C, E) and spa^- siblings (D, F) show large numbers of dct-positive cells in the posterior head at 25 hpf (C, D), but reduced numbers in spa^- embryos at 36 hpf (F; compare E). These melanoblasts remain more densely clustered, particularly just posterior to the otic vesicle (E, F). (G, H) Melanin and dct mark melanophores, whilst dct alone marks melanoblasts (white arrowhead) in the tail of wild types (G) and spa^- siblings (H) at 36 hpf. Note the paucity of ventral melanophores in mutant embryos. Scale bar: 200 μm (A, B), 75 μm (C, D), 100 μm (E, F), 75 μm (G, H).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kita^b5/b5 kita^tm63a
Observed In:	melanoblast melanocyte
Stage Range:	Prim-5 to Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 225(2), Kelsh, R.N., Schmid, B., and Eisen, J.S., Genetic analysis of melanophore development in zebrafish embryos, 277-293, Copyright (2000) with permission from Elsevier. Full text @ Dev. Biol.