FIGURE

Fig. 1

ID

ZDB-FIG-070815-26

Publication

French et al., 2007 - Pbx homeodomain proteins pattern both the zebrafish retina and tectum

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

The laminar structure of pbx2/4 null eyes is normal after 5 days of development. All laminar layers are present and in both wild type (A and B) and, and lzr mutants injected with pbx2/4 morpholinos (D and E). We note a consistent decrease in eye size in pbx2/4 null embryos, but the proportion of eye area occupied by the retinal pigmented epithelium in morphants is significantly increased (F verses C). The relative position of the optic nerve is similar in both wild type and morphant embryos. The retinal photoreceptor layer is absent in the ventral domain of the eye in lzr mutants injected with pbx2/4 morpholinos (I) when compared to wildtype (G) and is disorganized (compare H, wildtype, with J, lzr mutants injected with pbx2/4 morpholinos). Photoreceptor labeling was accomplished using the zpr-1 monoclonal antibody.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pbx4^b557/b557 + MO1-pbx2 + MO2-pbx4
Knockdown Reagents:	MO1-pbx2 MO2-pbx4
Observed In:	eye retinal neural layer retinal photoreceptor layer retinal photoreceptor layer ventral region
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.