FIGURE

Fig. S1

ID

ZDB-FIG-070613-41

Publication

Chocron et al., 2007 - Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points

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Fig. S1

Comparable nkx2.5 expression in laf/alk8 siblings (A) and mutant (B) embryos at the 15-somite stage. Heart tube in laf/alk8 siblings jogs to the left (C) while it remains in the middle in mutant embryos (D). Embryos at 28 hpf double stained with vmhc (red color) and amhc (blue color). laf/alk8 sibling (E) and mutant (F) embryos show absence of cardiac looping in the mutant embryo. (A–D) Dorsal views with anterior to the bottom of the panel. (E, F) Ventral views.

Expression Data

Genes:	myh6 myh7 myl7 nkx2.5
Fish:	acvr1l^{tm110b/tm110b} (TU) acvr1l^tm110b/+ (TU)
Anatomical Terms:	heart lateral plate mesoderm presumptive cardiac ventricle heart tube primitive heart tube
Stage Range:	14-19 somites to High-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	acvr1l^{tm110b/tm110b} (TU)
Observed In:	atrial cardiac muscle cell differentiation ventricular cardiac muscle cell differentiation
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 305(2), Chocron, S., Verhoeven, M.C., Rentzsch, F., Hammerschmidt, M., and Bakkers, J., Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points, 577-588, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.