FIGURE

Fig. 4

ID

ZDB-FIG-070416-4

Publication

Krock et al., 2007 - Noncell-autonomous photoreceptor degeneration in a zebrafish model of choroideremia

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Fig. 4

Opsin trafficking is unaffected in rep1 mutants. Retinal cryosections were stained with markers for rod and cone photoreceptors in wild type (A–D) and rep1 mutants (E–H). The 1D1 marker labels rhodopsin (Rho), whereas antibodies are against blue opsin (BOPS) and green opsin (GOPS) in the photoreceptor outer segments of wild-type and rep1 mutants. The zpr-1 antibody labels the red/green double cones and reveals the disheveled morphology of the photoreceptors. All sections were counterstained with DAPI to visualize nuclei. Pyknotic nuclei, a hallmark of cell death, are seen in rep1 mutants and indicated by arrows. (Scale bar, 20 μm.)

Expression Data

Genes:	opn1mw1 opn1sw2 rho
Fish:	WT chm^ru848/ru848
Anatomical Terms:	retinal cone cell retinal rod cell
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA