FIGURE

Fig. 8

ID

ZDB-FIG-070313-8

Publication

Lun et al., 1998 - A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary

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Fig. 8

Late marker gene expression during pharyngula stages in noi mutant embryos. Shown are lateral views, anterior to the left (except F-H: dorsal views). (A,B) no eng3 is seen in null mutants at 22 hours, whereas in the strong allele noi^th44a (C) a ventral eng3-positive spot can still be detected, and both ventral and dorsal expression is visible in weak noi^tb21 mutants (D,E); E, transverse section. (F-H) 24 hours. eng2 expression in the neural tube is absent in noi^tu29a; lateral expression in presumptive eye muscles is not affected. In the weak noi^ty31a allele ventral expression is seen, and is located, similar to the eng3 expression, in the ventral neural tube (I; transverse section). (J-M) Eng1 and her5 expression is completely absent at 26 hours.

Expression Data

Genes:	en1a en2a en2b her5
Fish:	WT pax2a^tb21/tb21 pax2a^th44/th44 pax2a^tu29a/tu29a pax2a^ty31a/ty31a
Anatomical Terms:	floor plate neural tube midbrain hindbrain boundary
Stage Range:	26+ somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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