Fig. 3
- ID
- ZDB-FIG-060113-3
- Publication
- Rohr et al., 2006 - Heart and soul/PRKCi and nagie oko/Mpp5 regulate myocardial coherence and remodeling during cardiac morphogenesis
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Nok is the functional homolog of mammalian Pals1/Mpp5. (A) noks305 mutant with ventrally curved body form and severely disrupted retinal pigmented epithelium at 34-36 hpf. (B) Wild type. (C) Murine Pals1/Mpp5 mRNA results in a partial phenotypic rescue of noks305 mutants, including the body form. (D) Wild-type retinal pigmented epithelium. (E) The noks305 retinal pigmented epithelium is severely disrupted. (F) Retinal pigmented epithelial cells are coherent in Pals1 mRNA-injected noks305 mutants (partial rescue). (G) A summary table showing the percentages of embryos with peripheral circulation among nok morphants injected with 50 ng/µl wild-type nok or 50 ng/µl Pals1/Mpp5 mRNA. |