FIGURE

Fig. 3

ID

ZDB-FIG-051209-4

Publication

Cooper et al., 2005 - Zebrafish foggy/spt5 is required for migration of facial branchiomotor neurons but not for their survival

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Fig. 3

foggy/spt5 is required cell-autonomously for facial branchiomotor neuron migration. A: Genetic mosaics were generated by transplanting cells from rhodamine dextran-labeled isl1-green fluorescent protein (GFP) transgenic donor cells to unlabeled hosts at gastrula stage (6 hours postfertilization [hpf]), and confocal images were collected at 36 hpf. Donor-derived cells are red, and donor derived motor neurons, which express GFP, are yellow. B: Wild-type facial motor neurons (arrow) migrate posteriorly in a wild-type host; n = 14 of 14. C: Wild-type facial motor neurons (arrows) also migrate posteriorly from rhombomere 4 (r4) in a foggy/spt5^fh20 mutant host, although to a lesser extent than in wild-type to wild-type control mosaics; n = 14 of 20. D: foggy/spt5^fh20 facial motor neurons (arrow) fail to migrate from r4 in a wild-type host; n = 11 of 11. Scale bar = 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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