FIGURE

Fig. 1

ID

ZDB-FIG-051123-1

Publication

Norton et al., 2005 - HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development

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Fig. 1

Phenotype of daedalus mutant embryos. (A,B) Dorsal views of live 5-day-old sibling (A) and dae mutant (B) larvae, anterior towards the left. dae mutants lack pectoral fins, but appear otherwise normal. (C,D) Alcian Blue staining of the pectoral fin endoskeleton. Wild-type endoskeleton (C) consists of a pectoral girdle, postcoracoid process and endoskeletal disk attached to the cleithrum. dae mutants (D) retain only a dysmorphic pectoral girdle and cleithrum. (E,F) Transverse cryosections of 40 hpf mutant and sibling embryos stained with Methylene Blue. Mutant embryos (F) have a smaller undifferentiated fin bud, without an apical ridge (ar, arrow), when compared with siblings (E). ed, endoskeletal disc; pp, postcoracoid process; sc, scapulocoracoid.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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