CRISPR

CRISPR1-setd5

ID

ZDB-CRISPR-240228-4

Name

CRISPR1-setd5

Previous Names

None

Target

Sequence

5' - GGGAGACACGAATTCGGCAA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "TGG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3885	setd5

Expression

Gene expression in Wild Types + CRISPR1-setd5

No data available

Phenotype

Phenotype resulting from CRISPR1-setd5

No data available

Phenotype of all Fish created by or utilizing CRISPR1-setd5

Phenotype	Fish	Conditions	Figures
brain dyrk1aa expression decreased amount, abnormal	setd5^zf3885/+	standard conditions	Figure 7 from Gabellini et al., 2022
social behavior process quality, abnormal	setd5^zf3885/+	standard conditions	Figure 5 , Figure 6 from Gabellini et al., 2022
brain homer1b expression decreased amount, abnormal	setd5^zf3885/+	standard conditions	Figure 7 from Gabellini et al., 2022
whole organism decreased weight, abnormal	setd5^zf3885/+	standard conditions	Figure 3 from Gabellini et al., 2022
telencephalon increased length, abnormal	setd5^zf3885/+	standard conditions	Figure 3 from Gabellini et al., 2022
developmental growth disrupted, abnormal	setd5^zf3885/+	standard conditions	Figure 4 from Gabellini et al., 2022
eye decreased area, abnormal	setd5^zf3885/+	standard conditions	Figure 4 from Gabellini et al., 2022
locomotory exploration behavior decreased process quality, abnormal	setd5^zf3885/+	standard conditions	Figure 5 from Gabellini et al., 2022
whole organism decreased length, abnormal	setd5^zf3885/+	standard conditions	Figure 3 , Figure 4 from Gabellini et al., 2022
brain nsd1b expression decreased amount, abnormal	setd5^zf3885/+	standard conditions	Figure 2 from Gabellini et al., 2022
social behavior process quality, ameliorated	setd5^zf3885/+	chemical treatment by environment: risperidone	Figure 6 from Gabellini et al., 2022
larval locomotory behavior decreased process quality, abnormal	setd5^zf3885/+	standard conditions	Figure 5 from Gabellini et al., 2022

Citations