CRISPR

CRISPR1-slc6a9

ID

ZDB-CRISPR-240221-7

Name

CRISPR1-slc6a9

Previous Names

None

Target

Sequence

5' - CCGTGGCGTATCGACCCTTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
chk1	slc6a9

Expression

Gene expression in Wild Types + CRISPR1-slc6a9

No data available

Phenotype

Phenotype resulting from CRISPR1-slc6a9

No data available

Phenotype of all Fish created by or utilizing CRISPR1-slc6a9

Phenotype	Fish	Conditions	Figures
vertebral column curvature, ameliorated	slc6a9^chk1/chk1 (TU)	chemical treatment by environment: sodium benzoate	Figure 6 from Wang et al., 2023
vertebral column curvature, ameliorated	slc6a9^chk1/chk1 (TU)	chemical treatment by environment: strychnine	Figure 6 from Wang et al., 2023
vertebral column curved lateral, abnormal	slc6a9^chk1/chk1 (TU)	standard conditions	Figure 4 , Figure 6 from Wang et al., 2023
vertebral column curved lateral, abnormal	slc6a9^chk1/+ (TU)	chemical treatment by environment: ALX 5407 hydrochloride	Figure 4 from Wang et al., 2023
vertebral column curved lateral, abnormal	slc6a9^chk1/+ (TU)	standard conditions	Figure 4 from Wang et al., 2023
spinal cord interneuron calcium(2+) bilateral symmetry, abnormal	slc6a9^chk1/chk1; jf5Tg	standard conditions	Figure 5 from Wang et al., 2023
spinal cord interneuron neuronal action potential decreased frequency, abnormal	slc6a9^chk1/chk1; jf5Tg	standard conditions	Figure 5 from Wang et al., 2023
spinal cord interneuron neuronal action potential spatial distribution of a process, abnormal	slc6a9^chk1/chk1; jf5Tg	standard conditions	Figure 5 from Wang et al., 2023

Citations