CRISPR

CRISPR1-tollip

ID

ZDB-CRISPR-221209-3

Name

CRISPR1-tollip

Previous Names

None

Target

tollip (1)

Sequence

5' - AGTGCAGTTAGACGCACAGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "CGG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
waw401	tollip

Expression

Gene expression in Wild Types + CRISPR1-tollip

No data available

Phenotype

Phenotype resulting from CRISPR1-tollip

No data available

Phenotype of all Fish created by or utilizing CRISPR1-tollip

Phenotype	Fish	Conditions	Figures
whole organism il1b expression increased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	chemical treatment by environment: lipopolysaccharide	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism tollip expression decreased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	standard conditions	Fig. 1 from Wolińska-Nizioł et al., 2022
whole organism ifnphi1 expression increased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	chemical treatment by environment: lipopolysaccharide	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism il10 expression increased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	control	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism Ab1-tollip labeling absent, abnormal	tollip^{waw401/waw401} (AB/TL)	standard conditions	Fig. 1 from Wolińska-Nizioł et al., 2022
whole organism nfkb2 expression increased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	control	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism tnfa expression increased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	chemical treatment by environment: lipopolysaccharide	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism il6 expression increased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	chemical treatment by environment: lipopolysaccharide	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism nfkbiaa expression increased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	chemical treatment by environment: lipopolysaccharide	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism il10 expression increased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	chemical treatment by environment: lipopolysaccharide	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism dead, abnormal	tollip^{waw401/waw401} (AB/TL)	chemical treatment by environment: lipopolysaccharide	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism mmp9 expression increased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	chemical treatment by environment: lipopolysaccharide	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism nfkb2 expression increased amount, abnormal	tollip^{waw401/waw401} (AB/TL)	chemical treatment by environment: lipopolysaccharide	Fig. 3 from Wolińska-Nizioł et al., 2022
whole organism swimming behavior decreased process quality, abnormal	gba1^sh391/sh391; tollip^{waw401/waw401} (AB/TL)	standard conditions	Fig. 4 from Wolińska-Nizioł et al., 2022

Citations