Gene

tollip

ID
ZDB-GENE-030131-8820
Name
toll interacting protein
Symbol
tollip Nomenclature History
Previous Names
  • fk22a02
  • im:7145391
  • wu:fk22a02
  • zgc:76985
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have ubiquitin binding activity and ubiquitin conjugating enzyme binding activity. Involved in negative regulation of Wnt signaling pathway. Predicted to localize to cytoplasm. Orthologous to human TOLLIP (toll interacting protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tollip Human Ortholog
No data available
Associated With tollip Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000008 C2 domain
Domain IPR003892 Ubiquitin system component CUE
Domain IPR037301 Toll-interacting protein, C2 domain
Domain IPR041799 Toll-interacting protein, CUE domain
Homologous_superfamily IPR009060 UBA-like superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length C2 domain C2 domain superfamily Toll-interacting protein, C2 domain Toll-interacting protein, CUE domain UBA-like superfamily Ubiquitin system component CUE
UniProtKB:Q7ZV43 276
UniProtKB:A0A0R4IVK4 252
UniProtKB:A0A0R4IZ33 276
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tollip-201 (1) Ensembl 918 nt
mRNA tollip-202 (1) Ensembl 1,305 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations