CRISPR

CRISPR1-alx3

ID

ZDB-CRISPR-220224-2

Name

CRISPR1-alx3

Previous Names

None

Target

alx3 (1)

Sequence

5' - GGCGTCCAACGGCTTGACTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
dco3003	alx3
dco3004	alx3

Expression

Gene expression in Wild Types + CRISPR1-alx3

No data available

Phenotype

Phenotype resulting from CRISPR1-alx3

No data available

Phenotype of all Fish created by or utilizing CRISPR1-alx3

Phenotype	Fish	Conditions	Figures
ethmoid cartilage increased length, abnormal	alx3^{dco3003/dco3003}	standard conditions	Fig. 4 from Mitchell et al., 2021
ethmoid cartilage decreased width, abnormal	alx3^{dco3003/dco3003}	standard conditions	Fig. 4 from Mitchell et al., 2021
parasphenoid decreased area, abnormal	alx3^{dco3003/dco3003}	standard conditions	Fig. 4 from Mitchell et al., 2021
ethmoid cartilage cell morphology, abnormal	alx3^{dco3003/dco3003} (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
parasphenoid absence of anatomical entity, abnormal	alx3^{dco3003/dco3003} (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage cartilaginous projection mislocalised, abnormal	alx3^{dco3003/dco3003} (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage increased length, abnormal	alx3^{dco3004/dco3004}	standard conditions	Fig. 4 from Mitchell et al., 2021
ethmoid cartilage decreased width, abnormal	alx3^{dco3004/dco3004}	standard conditions	Fig. 4 from Mitchell et al., 2021
parasphenoid decreased area, abnormal	alx3^{dco3004/dco3004}	standard conditions	Fig. 4 from Mitchell et al., 2021
ethmoid cartilage cartilaginous projection mislocalised, abnormal	alx3^dco3003/+ (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage cell morphology, abnormal	alx3^dco3003/+ (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage chondrocyte development premature, abnormal	alx3^{dco3003/dco3003}; sox9a^zc81Tg; vu234Tg	standard conditions	Fig. 6 from Mitchell et al., 2021
ethmoid cartilage chondrocyte increased amount, abnormal	alx3^{dco3003/dco3003}; sox9a^zc81Tg; vu234Tg	standard conditions	Fig. 6 from Mitchell et al., 2021
ethmoid cartilage chondrocyte development premature, abnormal	alx3^{dco3004/dco3004}; sox9a^zc81Tg; vu234Tg	standard conditions	Fig. 6 from Mitchell et al., 2021
ethmoid cartilage chondrocyte increased amount, abnormal	alx3^{dco3004/dco3004}; sox9a^zc81Tg; vu234Tg	standard conditions	Fig. 6 from Mitchell et al., 2021
ethmoid cartilage cartilaginous projection mislocalised, abnormal	tfap2a^ts213/+; alx3^dco3003/+ (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage cell morphology, abnormal	tfap2a^ts213/+; alx3^dco3003/+ (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
parasphenoid absence of anatomical entity, abnormal	tfap2a^ts213/+; alx3^dco3003/+ (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage cell morphology, abnormal	tfap2a^ts213/+; alx3^{dco3003/dco3003} (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
parasphenoid amount, ameliorated	tfap2a^ts213/+; alx3^{dco3003/dco3003} (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage cartilaginous projection mislocalised, exacerbated	tfap2a^ts213/+; alx3^{dco3003/dco3003} (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
parasphenoid mislocalised, abnormal	tfap2a^ts213/ts213; alx3^dco3003/+ (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage cartilaginous projection mislocalised, exacerbated	tfap2a^ts213/ts213; alx3^dco3003/+ (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
parasphenoid amount, exacerbated	tfap2a^ts213/ts213; alx3^dco3003/+ (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
eye cartilage tissue mislocalised, exacerbated	tfap2a^ts213/ts213; alx3^dco3003/+ (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage medial side split, exacerbated	tfap2a^ts213/ts213; alx3^dco3003/+ (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage cartilaginous projection mislocalised, exacerbated	tfap2a^ts213/ts213; alx3^{dco3003/dco3003} (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
ethmoid cartilage medial side split, exacerbated	tfap2a^ts213/ts213; alx3^{dco3003/dco3003} (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
parasphenoid mislocalised, exacerbated	tfap2a^ts213/ts213; alx3^{dco3003/dco3003} (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023
eye cartilage tissue mislocalised, exacerbated	tfap2a^ts213/ts213; alx3^{dco3003/dco3003} (AB)	standard conditions	Fig. 6. from Nguyen et al., 2023

Citations